A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydes.
نویسندگان
چکیده
A highly effective one-pot Friedländer quinoline synthesis using inexpensive reagents has been developed. o-Nitroarylcarbaldehydes were reduced to o-aminoarylcarbaldehydes with iron in the presence of catalytic HCl (aq.) and subsequently condensed in situ with aldehydes or ketones to form mono- or di-substituted quinolines in high yields (66-100%).
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 5 1 شماره
صفحات -
تاریخ انتشار 2007